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In 2010, a survey conducted all over the world says that more than 7 million humans around the world died of cancer. One in three women and one in two men developed cancer during their lifetime. About 15 percent of all deaths worldwide, was attributed to cancer. In some nations, cancer will surpass heart disease to become the most common cause of death. This paper attempts to demystify the behaviour of cancer-the defining plague of our generation. Here, we present a novel method based on silver nanoparticle-generated transient photothermal vapour nanobubbles. These intracellular plasmonic nanobubbles are effective in the diagnosis (by optical scattering) and treatment (by mechanical, nonthermal and selective destruction of target cells) of cancerous cells. Theoretical simulation of fused silica rod SPR sensors and optical fiber SPR sensors was carried out. Then these nanosensors were designed, fabricated and their sensitivities were measured experimentally. We introduce the nanosensors and describe how its size and environment can be harnessed to detect and treat cancer cells. This paper has been written from the quest to launch something that can eradicate this disease from our bodies and societies forever.