META 2021, META'12

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Theranostic and multiplexed dot immunoassay applications of Au/Ag nanocages and nanocomposites
Nikolai Khlebtsov, Boris Khlebtsov, Eliza Panfilova, Vitaly Khanadeev, Alexander Shirokov, Larisa Matora, Georgy Terentyuk

Last modified: 2011-12-09


We report two novel biomedical applications of Au/Ag alloy nanoparticles called nanocages. In the first case, composite nanoparticles consisting of a nanocage core and a mesoporous silica shell doped with a photodynamic sensitizer Yb-2,4-hematoporphyrin were fabricated, characterized, and tested in vitro and ex vivo. In the second part of the study, Ag nanocubes and Au/Ag nanocages bioconjugates were applied to a multiplexed dot immunoassay.


plasmonic nanoparticles, theranostics, nanocomposites, photodynamic therapy, biosensing, dot immunoassay