META 2021, META'12

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Monitoring cell metabolism using plasmon resonance energy transfer (PRET)
Olivier JF Martin

Last modified: 2011-12-09


Plasmon resonance energy transfer (PRET) can occur when a metalloprotein interacts strongly with a metallic metamaterial. In this contribution, we investigate the conditions that enhance this phenomenon and show how it can be used to monitor the production of reactive oxygen species in living cells. An unprecedented sensitivity is demonstrated, which enables monitoring living cells in environmental conditions and studying effects such as the toxicity associated to Cd(II) exposure.


sensing; metabolism; PRET