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The suitability and use of long-range surface plasmon-polaritons for biological and biochemical sensing is discussed. Emphasis is placed on sensors integrating metal stripe waveguides with microfluidic channels in straight and Mach-Zehnder interferometer geometries. Thiol-based chemistries and antibodies are used to render Au stripes selective to the target analyte. The sensing platform is capable of detecting analyte of mass within a very large range (from cells to proteins) with very competitive sensitivity and detection limit.

plasmons, sensors, biochemistry