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This talk will present our recent results on sensing and trapping with nano-apertures in metal films. Recently we have managed to trap single bovine serum albumin particles (a protein with hydrodynamic radius of 3.4 nm), and sense the trapping event with signal to noise ratio > 10. Continuing with sensing using hole-arrays, we have used engineering principles to reduce the noise and increase the signal to obtain sensitivity values comparable to large-scale commercial SPR sensors, but in an integration-friendly format for dense multiplexing.

plasmonics, sensors, optical tweezers